NexGard Safety Concerns

Are NexGard and similar products safe for your pet?

Have you seen the video circling social media sites recently of pets having seizures and discounting the safety of flea and tick prevention products such as NexGard, Bravecto and Simparica? Have you asked your pet’s vet about it and been told they still recommend these products? Do you wonder if your pets even need to have flea and tick prevention? What exactly does the FDA warning mean?

  • -The FDA warning is “alerting pet owners and veterinarians to be aware of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class.” However, “The FDA considers products in the isoxazoline class to be safe and effective for dogs and cats but is providing this information so that pet owners and veterinarians can take it into consideration when choosing flea and tick products for their pets.”

Essentially, the recent warning from the FDA is only requiring a change on package labeling for drugs in the entire isooxazoline class of drugs. Previously manufacturers listed possible side effects on the package insert but they will now be required to place possible neurological side effects in a more prominent location on the product.

Our veterinarians feel that NexGard and Bravecto are safe to administer to the vast majority of our patients. For pets that have history of seizures or do not meet other health requirements to take these products we offer Frontline Gold or Revolution as an alternative flea and tick prevention options. If you have any questions about whether these products are safe for your pet, please schedule an appointment to discuss your concerns with your pet’s veterinarian.

My pet is well taken care of, do they even need flea and tick prevention?

In Arizona 1 in 35 dogs tested positive for Ehrlichiosis, otherwise known as tick fever, in 2017. Symptoms of tick fever include: lethargy, fever, loss of appetite, weight loss and in severe cases lead to abnormal bleeding (nosebleeds or bleeding under the skin). Treatment can take several weeks and in progressed cases dogs may even need blood transfusions as part of their treatment. Other tick-borne diseases such as Lyme Disease and Anaplasmosis are not as common in Arizona but positive cases have been recorded each year.

Fleas can also transmit disease to our beloved furry family members. The most common conditions are flea allergy dermatitis and tapeworms. Tapeworms can also be transmitted to humans. Yuck! If enough fleas infest a pet, they can cause anemia from loss of blood. Young puppies and ill pets are at the highest risk for these infestations.

Lets review the facts:

  • -Before any drug (human or pet) can be put on the retail market the FDA requires rigorous safety studies to be performed. During the first few years that product is on the market they closely watch adverse reactions to ensure the product is safe when used in a larger population.
  • -Nexgard was launched 4 years ago, and to date has been sold in over 100 countries with 200 million doses sold. NexGard is the #1 product on the market for flea and tick prevention!
  • -According to BI, the maker of Nexgard, adverse reactions to their product are very rare less then 1 per 10,000 doses and this number includes other reactions such as vomiting, upset stomach, and lethargy.
  • The Scottsdale Veterinary Clinic has recommended Nexgard and Bravecto for hundreds of pets and used Nexgard as our primary flea and tick prevention in our boarding facility since its release and no pets within our care have developed any adverse neurological signs.
  • -With 1 in 35 dogs testing positive for tick borne diseases, flea and tick prevention is an essential part of your pet’s health routine.

We feel it is in the best interest of your pet to prevent these diseases from occurring by giving them flea and tick prevention each month!


If you would like to review the FDA warning you can find it at:

To see how prevalent tick associated diseases are in your area please visit: